{"product_id":"tocopherol-necklace-gold-vermeil","title":"tocopherol necklace | gold vermeil","description":"\u003ch2\u003eTocopherol necklace | 18K gold vermeil\u003c\/h2\u003e\n\u003cp\u003eThe molecule that protects every cell membrane from the chain-reaction oxidation that would otherwise propagate through it. Vitamin E, in 18K gold vermeil at 46 mm, the full chromanol head and the long isoprenoid tail that anchors the molecule into the lipid bilayer. The gold version of a milestone gift for someone whose work is about cellular protection.\u003c\/p\u003e\n\u003ch2 style=\"margin-top: 2em;\"\u003eThe Science Behind Tocopherol\u003c\/h2\u003e\n\u003cp\u003eTocopherol was discovered in 1922 by Herbert Evans and Katharine Bishop at UC Berkeley, originally as a dietary factor required for rat reproduction. The name comes from the Greek tokos (childbirth) and pherein (to bear). Alpha-tocopherol is the most active form, a lipophilic molecule that sits in cell membranes among the phospholipid tails. It functions as a chain-breaking antioxidant, donating a hydrogen atom to lipid peroxyl radicals and interrupting the chain reaction of lipid peroxidation through membrane phospholipids. The resulting tocopheroxyl radical is regenerated by ascorbate, part of an integrated antioxidant network. Vitamin E supplementation was tested in the HOPE and SELECT trials and showed no cardiovascular benefit, with some signal of harm at high doses.\u003c\/p\u003e\n\u003ch2 style=\"margin-top: 2em;\"\u003eWorn By\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ebiochemists and cell biologists studying oxidative stress\u003c\/li\u003e\n\u003cli\u003enutritional scientists and clinical dietitians who teach what supplementation does and does not do\u003c\/li\u003e\n\u003cli\u003eresearchers in lipid biochemistry or membrane biology marking a milestone\u003c\/li\u003e\n\u003cli\u003epartners and family of a working biochemist looking for a gold gift with a real molecule behind it\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOften paired with the silver counterpart at engagement-style milestones, where one half of the pair wears the silver and the other the gold.\u003c\/p\u003e\n\u003ch2 style=\"margin-top: 2em;\"\u003eExplore Related Molecules Jewelry\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/tocopherol\"\u003eTocopherol necklace | silver\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/anthocyanin\"\u003eAnthocyanin necklace | silver\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/chlorophyll\"\u003eChlorophyll necklace | silver\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/capsaicin\"\u003eCapsaicin necklace | silver\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/glucose-18k-gold-plated\"\u003eGlucose necklace | gold vermeil\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003csection class=\"product-faq\"\u003e\n\u003ch2 style=\"margin-top:2em;\"\u003eFAQ\u003c\/h2\u003e\n\u003ch3 style=\"margin-top:1.75em;\"\u003eWhy pick the gold version over the silver?\u003c\/h3\u003e\n\u003cp\u003eThe most common reason is the milestone framing. Gold reads as recognition where silver reads as daily wear. Same 46 mm pendant, same chain length, same molecule. The choice is about what the gift is meant to mark, not what tocopherol does. The two are sometimes given together: silver for the lab-bench daily piece, gold for the moment.\u003c\/p\u003e\n\u003ch3 style=\"margin-top:1.75em;\"\u003eWhy has Vitamin E supplementation failed in clinical trials when the chemistry is solid?\u003c\/h3\u003e\n\u003cp\u003eBecause the chemistry being correct in a test tube does not predict the supplement being beneficial in a person. The body already runs a coordinated antioxidant network, and dosing one component at unphysiological levels can disrupt the balance. The HOPE and SELECT trials found no cardiovascular benefit and some signal of harm at very high doses. The molecule is real. The supplementation as a public-health intervention is not.\u003c\/p\u003e\n\u003ch3 style=\"margin-top:1.75em;\"\u003eWhat size is the pendant and what is the return policy?\u003c\/h3\u003e\n\u003cp\u003e18K gold vermeil over a sterling silver core, 46 mm pendant on a 45 cm gold vermeil chain with a 5 cm extender. The full alpha-tocopherol structure renders large because of the chromanol head and the long isoprenoid tail. Nickel-free and hypoallergenic. Free worldwide DHL Express in 1-5 business days, with all import duties and taxes covered. 30-day “Love It or Return It” returns.\u003c\/p\u003e\n\u003ch3 style=\"margin-top:1.75em;\"\u003eIs there a silver version?\u003c\/h3\u003e\n\u003cp\u003eYes. The same 46 mm tocopherol pendant comes in \u003ca href=\"https:\/\/sciencejewelry1824.shop\/products\/tocopherol\"\u003esterling silver\u003c\/a\u003e at the same chain length. Same molecule, different metal, different occasion.\u003c\/p\u003e\n\u003c\/section\u003e\n","brand":"sciencejewelry1824","offers":[{"title":"Default Title","offer_id":56543803408770,"sku":"NK0368-GV","price":165.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1411\/4806\/files\/108_tocopherol_vermeil.png?v=1775799546","url":"https:\/\/sciencejewelry1824.shop\/products\/tocopherol-necklace-gold-vermeil","provider":"sciencejewelry1824","version":"1.0","type":"link"}