€ 170
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Estrogen necklace | sterling silver
Estrogen is the hormone with the widest brief in the body. Puberty and the menstrual cycle are the part everyone knows. Bone density, blood vessel tone, memory, mood and the growth of most breast cancers are the rest. A molecule with more say in daily life than its reputation suggests, in the form every chemistry student learns to draw.
The Chemistry of Estradiol
Estradiol was one of the hardest molecules of its era to get hold of. Edward Doisy's group needed four tons of sow ovaries to isolate 12 milligrams of it in 1936, seven years after Doisy and Adolf Butenandt had each pulled the weaker estrone out of pregnancy urine. Butenandt's Nobel Prize followed in 1939. The scarcity reflects the potency, since estradiol acts at picomolar concentrations. Every molecule of it begins as an androgen. Aromatase makes estradiol from testosterone by removing one methyl group and turning the A ring into a phenol. That phenolic ring is what sets the estrogens apart from every other steroid hormone, and what lets the molecule fit its receptor so tightly.
Worn By
- gynaecologists, reproductive endocrinologists and fertility specialists
- breast oncologists and researchers working on receptor-positive disease
- organic chemists and the students who learned steroid nomenclature on this ring system
- anyone marking menopause, fertility treatment or a hormonal chapter of their own life
Often given alongside the testosterone necklace, the two steroids that sit one aromatase step apart.
Explore Related Molecules Jewelry
- Estrogen necklace 3D | silver
- Estrogen necklace 3D | gold vermeil
- Testosterone necklace | silver
- Oxytocin necklace | silver
FAQ
Is this the right gift for someone in women's health?
Yes, and it tends to land best with people who work with the molecule rather than around it. A gynaecologist, an IVF specialist, a breast oncologist or an endocrinology fellow will read the structure at a glance. It also works as a personal piece for someone who has been through fertility treatment or menopause and wants to carry the chemistry of it on their own terms.
Why do men need estrogen at all?
Because it does jobs testosterone cannot do on its own. In 1994 doctors described a 28-year-old man whose estrogen receptor did not work. He was still growing, his growth plates had never closed, and his bones were thin. Estradiol, made locally from testosterone by aromatase, is what closes the growth plates in both sexes and keeps adult bone dense. It also has a hand in male libido and sperm maturation.
What size, material and chain?
32 mm pendant in 925 polished sterling silver, nickel-free and hypoallergenic. 45 cm sterling silver chain with 5 cm extender. Ships free worldwide via DHL Express in 1-5 business days, with all import duties and taxes covered. Comes in a ready-to-gift eco-friendly box with the 30-day “Love It or Return It” policy.
How is the flat estrogen different from the 3D estrogen necklace?
Two different designs of the same molecule. The flat pendant is the skeletal formula of estradiol in two dimensions, the way it is written on a whiteboard or in a textbook. The 3D pendant is the molecular geometry, at 38 mm. The flat version comes in sterling silver, the 3D version in silver and gold vermeil. Chain and shipping are the same for both.
Molecules
Delve into the hidden elegance of science with our meticulously crafted jewelry, inspired by the intricate structures of chemical molecules. Each piece serves as a tactile tribute to the building blocks of life and matter, capturing the allure of atoms and bonds in precious metals. A harmonious fusion of art and science, these creations are more than mere accessories; they're a celebration of the enigmatic beauty that underpins our universe.
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