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Ketamine propofol necklace H | sterling silver
Ketofol is the name emergency medicine gave to ketamine and propofol given together. A ketamine propofol necklace makes a gift for the woman in your life who runs those sedations, or something to keep if you run them yourself.
Who It's For
- an emergency physician who sedates patients for painful procedures
- an anaesthetist, or a trainee in anaesthesia or intensive care
- a nurse on the sedation team
- yourself, if procedural sedation is part of your work
Haris E., who bought it as a gift: “Excellent quality, nice size, arrived early than the estimated delivery date.”
Why Ketamine and Propofol Are Mixed
The two drugs work on different receptors in the brain. Ketamine blocks the NMDA receptor, a gate for the signalling molecule glutamate, and propofol is thought to work mainly by strengthening GABA-A receptors. Their side effects pull in opposite directions. Propofol can lower blood pressure and slow breathing, while ketamine tends to raise blood pressure and heart rate and largely preserves protective airway reflexes. Ketamine on its own can cause vomiting and unpleasant reactions on waking, such as vivid dreams, and propofol works against nausea. In the best-known emergency studies they were mixed 1:1 in one syringe, so each drug can be given at a lower dose. At least, that is the idea.
Explore Related Anaesthesia Jewelry
- ketamine propofol necklace H | gold vermeil
- ketamine propofol necklace V | silver
- propofol necklace | silver
- ketamine necklace | silver
FAQ
How big is the pendant, and how does it sit?
The pendant measures 38 mm (about 1.5 inches), about 12 mm more than the width of a 2-euro coin (25.75 mm). The chain is attached to the pendant at both ends, so it lies across the neckline and cannot be moved to another chain. It sits below the collarbone. The chain is 45 cm (17.7 inches) long, with a lobster clasp and a 5 cm (2 inch) extender. Our sterling silver is 925, nickel-free and hypoallergenic. If it darkens over time, a soft polishing cloth brings it back.
Is there a gold vermeil version, or a vertical one?
Yes to both. This horizontal necklace also comes in 18K gold vermeil, and there is a vertical version in sterling silver and in gold vermeil. All four have a 38 mm pendant on a 45 cm chain with extender. The vertical pendant hangs from the chain at a single point, so it sits upright. Choose the finish she already wears: silver and gold vermeil carry the same design. For one drug on its own, there are propofol (22 mm) and ketamine (27 mm) necklaces in both finishes.
Will it arrive in time, and what if it isn't right?
DHL Express delivers free in 1-5 business days worldwide, and we pay the import duties and taxes, so nothing is due at the door. It arrives in a ready-to-gift jewelry box and festive envelope. If it isn't right, our 30-day “Love It or Return It” policy applies.
Is ketofol safer than propofol alone?
The evidence is mixed. In 2007, Willman and Andolfatto, of the University of British Columbia, reported 114 emergency sedations with ketofol in which no patient developed low blood pressure or vomited. Their group then ran a double-blind trial in 284 patients, published in 2012. Respiratory events, such as low oxygen, were not reduced: 30 per cent with ketofol against 32 per cent with propofol alone, though sedation depth was steadier with the mix. A 2015 review pooling five trials found fewer events with ketofol, 29 against 35 per cent.
Molecules
Delve into the hidden elegance of science with our meticulously crafted jewelry, inspired by the intricate structures of chemical molecules. Each piece serves as a tactile tribute to the building blocks of life and matter, capturing the allure of atoms and bonds in precious metals. A harmonious fusion of art and science, these creations are more than mere accessories; they're a celebration of the enigmatic beauty that underpins our universe.
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Necklace length guide
