€ 150
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Nucleosomes necklace | sterling silver
The fundamental unit of chromatin packaging — DNA wrapped around a histone core, the first level in the organisation of a genome.
The Science of Nucleosomes
A nucleosome consists of 147 base pairs of DNA wrapped 1.65 times around a histone octamer — two copies each of H2A, H2B, H3, and H4. Adjacent nucleosomes are connected by linker DNA and can be further compacted with the help of histone H1. The structure serves dual purposes: reducing the physical length of DNA (the ~2 metres of human DNA must fit into a nucleus 6 µm in diameter) and regulating gene expression. Post-translational modifications to histone tails — acetylation, methylation, phosphorylation — alter chromatin compaction and recruit transcriptional regulators, forming part of the epigenetic code.
A Meaningful Gift for Science Lovers
A piece for molecular biologists, epigenetics researchers, and anyone working at the interface of DNA and gene regulation.
- For the molecular biologist or epigenetics researcher who works with chromatin
- For a geneticist or genome biologist who thinks about chromatin structure
- For a biochemistry student who has worked through histone modification pathways
- As a distinctive piece connecting the science of how genomes are organised
Comes in a gift box. Free worldwide shipping.
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FAQ
Q: Who would value a nucleosomes necklace?
A: Structural biologists, epigeneticists, chromatin researchers, or anyone fascinated by how DNA is organized and regulated. A subtle way to wear one of biology's most elegant nanomachines.
Q: Could a histone mutation disrupt an entire organism?
A: Yes. Histone mutations are increasingly recognized as oncogenic drivers. Mutations in H3.3 drive certain pediatric gliomas; H2B mutations appear in various cancers. A single histone variant can cascade through gene expression patterns across entire cell populations.
Q: What size and material?
A: 28 mm pendant in sterling silver (925, rhodium-plated) on a 45 cm silver chain with lobster clasp. Hypoallergenic, nickel-free. Free DHL shipping worldwide.
Q: Is there a gold version?
A: Yes. The nucleosomes necklace is also available in 18k gold vermeil. Both versions are covered by our 30-day return policy.
Cellular Biology
Step into the fascinating world of cellular biology through our unique jewelry designs. These pieces serve as wearable reflections of life's microscopic wonders, capturing the aesthetics of DNA strands, cellular formations, and more. Far from simple adornments, they spark dialogue and honor the captivating complexities found within biological research. Merging scientific accuracy with artistic flair, each creation offers a tactile experience that bridges the gap between scientific inquiry and aesthetic appreciation.
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